New novel non-MHC genes were identified for cervical cancer with an integrative analysis approach of transcriptome-wide association study
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چکیده
منابع مشابه
Epigenome-wide association study and integrative analysis with the transcriptome based on GWAS summary statistics
The past decade has seen a rapid growth in omics technologies. Genome-wide association studies (GWAS) have uncovered susceptibility variants for a variety of complex traits. However, the functional significance of most discovered variants are still not fully understood. On the other hand, there is increasing interest in exploring the role of epigenetic variations such as DNA methylation in dise...
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15 صفحه اولGenome-wide association study of susceptibility loci for cervical cancer.
BACKGROUND Cervical carcinoma has a heritable genetic component, but the genetic basis of cervical cancer is still not well understood. METHODS We performed a genome-wide association study of 731 422 single nucleotide polymorphisms (SNPs) in 1075 cervical cancer case subjects and 4014 control subjects and replicated it in 1140 case subjects and 1058 control subjects. The association between t...
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ژورنال
عنوان ژورنال: Journal of Cancer
سال: 2021
ISSN: 1837-9664
DOI: 10.7150/jca.47918